Presentation of the Galilee Institute
I. Presentation
The Galilée Institute, a component of Paris 13 University, is a scientific Centre that brings together undergraduate and graduate programs, an engineering school – Sup-Galilée – and seven research laboratories. This original structure allows increasing the necessary synergy between research, general training and professional and technological training, offering our students the best lectures.
The laboratories of the Galilée Institute conduct innovative and high-level research in a broad spectrum of scientific fields ranging from mathematics to chemistry, through computer science, physics, engineering and materials sciences, and bio-materials. They are almost all associated with major research organizations (CNRS and INSERM). They exhibit a strong influence at the national and international levels, as evidenced by the results of the regular national assessments and their participation in six Laboratories of Excellence (LABEX) and Equipment of Excellence (EQUIPEX), both supported by the government program “Investments for the future”.
At all levels, the professional integration of its students is one of the major concerns of the Galilée Institute. A Sup-Galilée Corporate Forum and an alternation forum are organized every year; many partnerships with companies are signed. This orientation has been strengthened in recent years. In addition, our researchers and students can benefit from the Incub’13 Incubator’s supervision to develop business creation activities.
Moreover, in order to best prepare its students for the world of tomorrow in all its diversity, many actions are carried out to facilitate international exchanges.
Dynamism of research and teaching, active partnership with companies, international visibility such are the strengths of the Galilée Institute that are strengthen each year.
II. Research in Galilée Institute
The Galilée Institute houses 7 laboratories:
CSPBAT – LABORATORY OF CHEMISTRY, STRUCTURE AND PROPERTIES OF BIOMATERIALS AND THERAPEUTIC AGENTS (CNRS-UMR 7244)
Scientific goal of team 1 (V. Migonney):
The expertise of the team is the synthesis, development, and functionalization of biomaterials. To do this we make “model” or “prosthetic” surfaces and evaluate their properties and development possibilities. The latest projects we have started recently and will continue are:
– radical synthesis of controlled architectures and the influence of such structures on biological responses
– functionalization of ceramic surfaces – collaboration with an industrial partner (ICERAM)
– development of biodegradable bioactive structures of interest in surgical applications (orthopedic, obstetric, dental)
Scientific goal of team 2 (M. Lecouvey):
While very promising, the anticancer activity of bisphosphonates is hampered by their poor bioavailability in the organism. This major drawback is due to their poor lipophilicity, their highly charged nature and their propensity to chelate divalent cations such as calcium and magnesium in the gastrointestinal tract. To overcome this problem, different exciting strategies are developed in the team:
– The development of lipophilic ester prodrugs
– The development of new vectors (nitrogen-containing bisphosphonate covalently coupled to a polysaccharidic polymer)
Scientific goal of team 3 (M. Salerno / J. Spadavecchia) The main objective of our team is to develop an original approach as well as the answer to important scientific and industrial concerns of the moment, by means of an intrinsically multidisciplinary subject of research. The goal of the two axes developed is to bring a global coherence in the field of nanomedicine and healthcare.
– Development of Hybrid Nanoparticles: From conception to characterization of new nanovectors
– Spectroscopic approach for biomarkers studies, understanding pathological mechanisms at the cellular level
– Metabolomics studies
L2TI – Information Processing and Transport Laboratory (EA3043)
LAGA – Analysis, Geometry & Applications Laboratory (CNRS-UMR 7539)
LIPN – Paris Nord Computer Science Laboratory (CNRS-UMR 7030)
The department is structured into five research teams, each on one or several of these research areas. Among the 150 people working at LIPN, 87 hold a permanent position at the University. LIPN is a member of the MathSTIC federation, a center for research in Mathematics, Computer Science, and Information technology.
LPL – Laboratory of Physics of Lasers (CNRS – UMR7538)
LSPM – Laboratory of Sciences of Processes and Materials (CNRS-UPR3407)
LVTS – Translational Vascular Research Laboratory (INSERM U1148)
The laboratories are locally organized around two research poles:
– MathSTIC dedicated to mathematics, computer and information sciences and technologies, bringing together the LAGA, LIPN and L2TI laboratories
– Experimental Sciences dedicated to physics, chemistry, process engineering, material sciences, life sciences, bringing together the LPL, LSPM, CSPBAT and LVTS laboratories.
Nearly 200 students are pursuing their doctoral studies in our laboratories under the auspices of the Galilée doctoral school of Paris 13 University. These students are issued from our masters or coming from outside our institute. We welcome a large number of foreign PhD students in the framework of numerous international collaborative projects.
The visibility of our research internationally is also reflected through welcoming a large number of visiting professors in our different laboratories.